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Unit Virologie et Immunologie Moléculaires

article

04 April 2024

By: Service de presse INRAE, Direction de la communication EnvA

COVID-19: A potential treatment for loss of smell

COMMUNIQUÉ DE PRESSE - L’un des symptômes persistants et invalidants de la Covid-19 est la perte de l'odorat (ou anosmie). Des scientifiques d’INRAE et de l’EnvA ont montré l'efficacité des corticoïdes dans la restauration des capacités olfactives impactées suite à l’infection virale. Ces résultats, parus le 27 février dans Brain, Behavior, and Immunity, marquent une avancée importante dans la compréhension et le traitement de ce symptôme.
article

04 April 2024

By: INRAE press office

Probing the protein used by SARS-CoV-2 to infect cells

PRESS RELEASE - To cause infection, viruses must enter the cells of their hosts. Viruses thus sport proteins on their membrane surfaces that allow their membranes to fuse with those of host cells. In collaboration with researchers at Cornell University in the US, INRAE researchers characterised a key surface protein found in SARS-CoV-2, the virus responsible for COVID-19. The group discovered that SARS-CoV-2 possesses a surface protein that is distinct from the surface proteins of other closely related coronaviruses. This difference in surface proteins might have played an important role in the evolution and emergence of SARS-CoV-2. These findings were recently published in the Journal of Molecular Biology.
© INRAE

As the COVID-19 epidemic spreads throughout the world, the research community is mobilising its forces. In the Paris region, INRAE researchers Jean-François Eléouët and Bernard Delmas and their teams in the Molecular Virology and Immunology Unit (VIM) are hard at work: their aim is to accelerate their knowledge, prevent and cure the disease; each new goal corresponds to a new research project.

© INRAE

Developed in the context of the European SAPHIR project, a vaccine against bovine respiratory syncytial virus, effective after one dose, has proved its efficacy in young cattle. An associated DIVA test reinforces the usefulness of this vaccine.

Our colleagues from zebrafish phenotyping platform recently attended MiFoBio microscopy meeting. Taking with them freshly clarified rainbow trout (4g) provided by IERP, they had the opportunity to image the whole specimen on an home made Optical Projection Tomography (OPT) microscope.