Publications of our group:
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Simoneau S, Igel A, Ciric D, Moudjou M, Tcherniuk S, Béringue V, Rezaei H & Flan B. Characterization of the 263K-derived microsomal fraction: a source of prions for nanofiltration validation studies. Transfusion (Paris). 2024 may; trf.17860.

Marín-Moreno A, Reine F, Herzog L, Aron N, Jaffrézic F, Vilotte J-L, Rezaei H, Andréoletti O, Martin D & Béringue V. Assessment of the zoonotic potential of atypical scrapie prions in humanized mice reveals rare phenotypic convergence but not identity with sporadic CJD prions. J. Infect. Dis. 2024 feb; jiae093.


Bohl J, Moudjou M, Herzog L, Reine F, Sailer F, Klute H, Halgand F, Rest GV der, Boulard Y, Béringue V, Igel A & Rezaei H. The Smallest Infectious Substructure Encoding the Prion Strain Structural Determinant Revealed by Spontaneous Dissociation of Misfolded Prion Protein Assemblies. J. Mol. Biol. 2023 nov; 435(21), 168280.

Diot C, Richard C-A, Risso-Ballester J, Martin D, Fix J, Eléouët J-F, Sizun C, Rameix-Welti M-A & Galloux M. Hardening of Respiratory Syncytial Virus Inclusion Bodies by Cyclopamine Proceeds through Perturbation of the Interactions of the M2-1 Protein with RNA and the P Protein. Int. J. Mol. Sci. 2023 Sept; 24(18), 13862.

Igel A, Fornara B, Rezaei H & Béringue V. Prion assemblies: structural heterogeneity, mechanisms of formation, and role in species barrier. Cell Tissue Res. 2023 April; 392, 149–166.


Vidal E, Sánchez-Martín MA, Eraña H, Lázaro SP, Pérez-Castro MA, Otero A, Charco JM, Marín B, López-Moreno R, Díaz-Domínguez CM, et al. Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model. Acta Neuropathol. Commun. 2022 dec; 10(1), 179.

Dong J, Basse V, Bierre M, Peres de Oliveira A, Vidalain P-O, Sibille P, Tangy F, Galloux M, Eleouet J-F, Sizun C & Bajoreek M. Respiratory Syncytial Virus NS1 Protein Targets the Transactivator Binding Domain of MED25. J. Mol. Biol. 2022 Oct; 434(19), 167763.

Hannaoui S, Zemlyankina I, Chang SC, Arifin MI, Béringue V, McKenzie D, Schatzl HM & Gilch S. Transmission of cervid prions to humanized mice demonstrates the zoonotic potential of CWD. Acta Neuropathol. (Berl.) 2022; 144(4), 767–784.


Panes J-D, Saavedra P, Pineda B, Escobar K, Cuevas M-E, Moraga-Cid G, Fuentealba J, Rivas C-I, Rezaei H & Muñoz-Montesino C. PrP C as a Transducer of Physiological and Pathological Signals. Front. Mol. Neurosci. 2021 Nov; 14, 762918.

Moazami-Goudarzi K, Andréoletti O, Vilotte J L & Béringue V. Review on PRNP genetics and susceptibility to chronic wasting disease of Cervidae. Vet. Res. 2021 Oct; 52(1): e128.

Douet J Y, Huor A, Cassard H, Lugan S, Aron N, Mesic C, Vilette D, Barrio T, Streichenberger N, Perret-Liaudet A, Delisle M B, Péran P, Deslys J P, Comoy E, Vilotte J L, Goudarzi K, Béringue V, Barria M A, Ritchie D L, Ironside J W & Andréoletti O. Prion strains associated with iatrogenic CJD in French and UK human growth hormone recipients. Acta Neuropathol. Commun. 2021 Aug; 9(1): e145.

Martin D, Reine F, Herzog L, Igel-Egalon A, Aron N, Michel C, Moudjou M, Fichet G, Quadrio I, Perret-Liaudet A, Andréoletti O, Rezaei H & Béringue V. Prion potentiation after life-long dormancy in mice devoid of PrP. Brain Commun. 2021 Apr; 3(2): fcab092.

Zhang W, Xiao X, Ding M, Yuan J, Foutz A, Moudjou M, Kitamoto T, Langeveld J P M, Cu L & Zou W Q. Further Characterization of Glycoform-Selective Prions of Variably Protease-Sensitive Prionopathy. Pathog. Basel Switz. 2021 Apr; 10(5): e513.

Bamia A, Sinane M, Naït-Saïdi R, Dhiab J, Keruzoré M, Nguyen P H, Bertho A, Soubigou F, Halliez S, Blondel M, Trollet C, Simonelig M, Friocourt G, Béringue V, Bihel F & Voisset C. Anti-prion Drugs Targeting the Protein Folding Activity of the Ribosome Reduce PABPN1 Aggregation. Neurother. J. Am. Soc. Exp. Neurother. 2021 Apr; 18(2): 1137–1150.

Castille J, Passet B, Makhzami S, Vilotte M, Moazami-Goudarzi K, Truchet S, Daniel-Carlier N, Gaillard A L, Andréoletti O, Vaiman D, Beauvallet C, Vaiman A, Floriot S, Calvel P, Mouillet-Richard S, Duchesne A, Béringue V & Vilotte J L. Co-invalidation of Prnp and Sprn in FVB/N mice affects reproductive performances and highlight complex biological relationship between PrP and Shadoo. Biochem. Biophys. Res. Commun. 2021 Apr; 551: 1–6.

Waeytens J, Mathurin J, Deniset-Besseau A, Arluison V, Bousset L, Rezaei H, Raussens V & Dazzi A. Probing amyloid fibril secondary structures by infrared nanospectroscopy: experimental and theoretical considerations. The Analyst. 2021 Jan; 146(1), 132–145.


Moudjou M, Castille J, Passet B, Herzog L, Reine F, Vilotte J L, Rezaei H, Béringue V & Igel-Egalon A. Improving the Predictive Value of Prion Inactivation Validation Methods to Minimize the Risks of Iatrogenic Transmission With Medical Instruments. Front. Bioeng. Biotechnol. 2020 Dec; 8: e591024.

Munoz-Montesino C, Larkem D, Barbereau C, Igel-Egalon A, Truchet S, Jacquet E, Nhiri N, Moudjou M, Sizun C, Rezaei H, Béringue V & Dron M. A seven-residue deletion in PrP leads to generation of a spontaneous prion formed from C-terminal C1 fragment of PrP. J. Biol. Chem. 2020 Oct; 295(41): 14025–14039.

Huin C, Cronier S, Guégan P, Béringue V, Rezaei H & Noinville S. Conformation-dependent membrane permeabilization by neurotoxic PrP oligomers: The role of the H2H3 oligomerization domain. Arch. Biochem. Biophys. 2020 Oct; 692: e108517.

Bohl J, Sicard C, Rezaei H, Van der Rest G & Halgand F. Evidence of conformational landscape alteration and macromolecular complex formation in the early stages of in vitro human prion protein oxidation. Arch. Biochem. Biophys. 2020 Sept; 690: e108432.

Lévy E, Jaffrézic F, Laloë D, Rezaei H, Huang M E, Béringue V, Martin D & Vernis L. PiQSARS: A pipeline for quantitative and statistical analyses of ratiometric fluorescent biosensors. MethodsX 2020 Aug; 7: e101034.

Béringue V, Tixador P, Andréoletti O, Reine F, Castille J, Laï T L, Le Dur A, Laisné A, Herzog L, Passet B, Rezaei H, Vilotte J & Laude H. Host prion protein expression levels impact prion tropism for the spleen. PLoS Pathog. 2020 July; 16(7): e1008283.

Igel-Egalon A, Laferrière F, Tixador P, Moudjou M, Herzog L, Reine F, Torres J M, Laude H, Rezaei H & Béringue V. Crossing Species Barriers Relies on Structurally Distinct Prion Assemblies and Their Complementation. Mol. Neurobiol. 2020 June; 57(6): 2572–2587.

Cassard H, Huor A, Espinosa J C, Douet J Y, Lugan S, Aron N, Vilette D, Delisle M B, Marín-Moreno A, Peran P, Beringue V, Torres J M, Ironside J W & Andreoletti O. Prions from Sporadic Creutzfeldt-Jakob Disease Patients Propagate as Strain Mixtures. mBio 2020 June; 11(3): e00393-20.

Passet B, Castille J, Makhzami S, Truchet S, Vaiman A, Floriot S, Moazami-Goudarzi K, Vilotte M, Gaillard A L, Helary L, Bertaud M, Andréoletti O, Vaiman D, Calvel P, Daniel-Carlier N, Moudjou M, Beauvallet C, Benharouga M, Laloé D, Mouillet-Richard S, Duchesne A, Béringue V & Vilotte J L. The Prion-like protein Shadoo is involved in mouse embryonic and mammary development and differentiation. Sci. Rep. 2020 Apr; 10(1): e6765.

La Rosa C, Condorelli M, Compagnini G, Lolicato F, Milardi D, Do T N, Karttunen M, Pannuzzo M, Ramamoorthy A, Fraternali F, Collu F, Rezaei H, Strodel B & Raudino A. Symmetry-breaking transitions in the early steps of protein self-assembly. Eur. Biophys. J. EBJ 2020 March; 49(2): 175–191.

Barrio T, Filali H, Otero A, Sheleby-Elías J, Marín B, Vidal E, Béringue V, Torres J M, Groschup M, Andréoletti O, Badiola J J & Bolea R. Mixtures of prion substrains in natural scrapie cases revealed by ovinised murine models. Sci. Rep. 2020 Mar; 10(1): e5042.

Bélondrade M, Jas-Duval C, Nicot S, Bruyère-Ostells L, Mayran C, Herzog L, Reine F, Torres J M, Fournier-Wirth C, Béringue V. Lehmann S & Bougard D. Correlation between Bioassay and Protein Misfolding Cyclic Amplification for Variant Creutzfeldt-Jakob Disease Decontamination Studies. mSphere 2020 Jan; 5(1): e00649-19.


Doumic M, Fellner K, Mezache M & Rezaei H. A bi-monomeric, nonlinear Becker-Döring-type system to capture oscillatory aggregation kinetics in prion dynamics. J. Theor. Biol. 2019 Nov; 480: 241–261.

Igel-Egalon A, Laferrière F, Moudjou M, Bohl J, Mezache M, Knäpple T, Herzog L, Reine F, Jas-Duval C, Doumic M, Rezaei H & Béringue V. Early stage prion assembly involves two subpopulations with different quaternary structures and a secondary templating pathway. Commun. Biol. 2019 Oct; 2.

Al-Dybiat I, Moudjou M, Martin D, Reine F, Herzog L, Truchet S, Berthon P, Laude H, Rezaei H, Andréoletti O, Béringue V & Sibille P. Prion strain-dependent tropism is maintained between spleen and granuloma and relies on lymphofollicular structures. Sci. Rep. 2019 Oct; 9(1): e14656.

Wang Z, Yuan J, Shen P, Abskharon R, Lang Y, Dang J, Adornato A, Xu L, Chen J, Feng J, Moudjou M, Kitamoto T, Lee H G, Kim Y S, Langeveld J, Appleby B, Ma J, Kong Q, Petersen R B, Zou W Q & Cui L. Correction to: In Vitro Seeding Activity of Glycoform-Deficient Prions from Variably Protease-Sensitive Prionopathy and Familial CJD Associated with PrPV180I Mutation. Mol. Neurobiol. 2019 Aug; 56(8): 5470.

Wang Z, Yuan J, Shen P, Abskharon R, Lang Y, Dang J, Adornato A, Xu L, Chen J, Feng J, Moudjou M, Kitamoto T, Lee H G, Kim Y S, Langeveld J, Appleby B, Ma J, Kong Q, Petersen R B, Zou W Q & Cui L. In Vitro Seeding Activity of Glycoform-Deficient Prions from Variably Protease-Sensitive Prionopathy and Familial CJD Associated with PrPV180I Mutation. Mol. Neurobiol. 2019 Aug; 56(8): 5456–5469.

Van der Rest G, Rezaei H & Halgand F. Transient multimers modulate conformer abundances of prion protein monomer through conformational selection. Sci. Rep. 2019 Aug; 9(1): e12159.

Lévy E, El Banna N, Baïlle D, Heneman-Masurel A, Truchet S, Rezaei H, Huang M-E, Béringue V, Martin D & Vernis L. Causative Links between Protein Aggregation and Oxidative Stress: A Review. Int. J. Mol. Sci. 2019 Aug; 20(16): e3896.

Igel-Egalon A, Bohl J, Moudjou M, Herzog L, Reine F, Rezaei H & Béringue, V. Heterogeneity and Architecture of Pathological Prion Protein Assemblies: Time to Revisit the Molecular Basis of the Prion Replication Process? Viruses 2019 May; 11(5): e429.

Hirsch T Z, Martin-Lannerée S, Reine F, Hernandez-Rapp J, Herzog L, Dron M, Privat N, Passet B, Halliez S, Villa-Diaz A, Lacroux C, Klein V, Haïk S, Andréoletti O, Torres J-M, Vilotte J-L, Béringue V & Mouillet-Richard S. Epigenetic Control of the Notch and Eph Signaling Pathways by the Prion Protein: Implications for Prion Diseases. Mol. Neurobiol. 2019 March; 56(3): 2159–2173.

Torrent J, Martin D, Noinville S, Yin Y, Doumic M, Moudjou M, Béringue V & Rezaei H. Pressure Reveals Unique Conformational Features in Prion Protein Fibril Diversity. Sci. Rep. 2019 Feb; 9(1): e2802.

Marín-Moreno A, Aguilar-Calvo P, Moudjou M, Espinosa J C, Béringue V & Torres J M. Thermostability as a highly dependent prion strain feature. Sci. Rep. 2019 Aug; 9(1): e11396.

Torrent J, Martin D, Igel-Egalon A, Béringue V & Rezaei H. High-Pressure Response of Amyloid Folds. Viruses 2019 Feb; 11(3): e202.

Combet S, Cousin F, Rezaei H & Noinville S. Membrane interaction of off-pathway prion oligomers and lipid-induced on-pathway intermediates during prion conversion: A clue for neurotoxicity. Biochim. Biophys. Acta Biomembr. 2019 Feb; 1861(2), 514–523.

Helal M, Igel-Egalon A, Lakmeche A, Mazzocco P, Perrillat-Mercerot A, Pujo-Menjouet L, Rezaei H & Tine L M. Stability analysis of a steady state of a model describing Alzheimer’s disease and interactions with prion proteins. J. Math. Biol. 2019 Jan; 78(1-2): 57–81.


Collu F, Spiga E, Chakroun N, Rezaei H & Fraternali F. Probing the early stages of prion protein (PrP) aggregation with atomistic molecular dynamics simulations. Chem. Commun. Camb. Engl. 2018 July; 54(57): 8007–8010.

Ragagnin A, Ezpeleta J, Guillemain A, Boudet-Devaud F, Haeberle A M, Demais V, Vidal C, Demuth S, Beringue V, Kellermann O, Schneider B, Grant N J & Bailly Y. Cerebellar compartmentation of prion pathogenesis. Brain Pathol 2018 Mar; 28(2): 240-263.

Igel-Egalon A, Beringue V, Rezaei H & Sibille P. Prion Strains and Transmission Barrier Phenomena. Pathogens 2018 Jan; 7(1): 5.


Privat N, Levavasseur E, Yildirim S, Hannaoui S, Brandel J P, Laplanche J L, Beringue V, Seilhean D & Haik S. Region-specific protein misfolding cyclic amplification reproduces brain tropism of prion strains. J Biol Chem. 2017 Oct 06; 292(40): 16688-16696.

Igel-Egalon A, Moudjou M, Martin D, Busley A, Knapple T, Herzog L, Reine F, Lepejova N, Richard C A, Beringue V & Rezaei H. Reversible unfolding of infectious prion assemblies reveals the existence of an oligomeric elementary brick. PLoS Pathog. 2017 Sep; 13(9): e1006557.

Armiento A, Moireau P, Martin D, Lepejova N, Doumic M & Rezaei H. The mechanism of monomer transfer between two structurally distinct PrP oligomers. PLoS One. 2017 12(7): e0180538.

Douet J Y, Lacroux C, Aron N, Head M W, Lugan S, Tillier C, Huor A, Cassard H, Arnold M, Beringue V, Ironside J W & Andreoletti O. Distribution and Quantitative Estimates of Variant Creutzfeldt-Jakob Disease Prions in Tissues of Clinical and Asymptomatic Patients. Emerg Infect Dis. 2017 Jun; 23(6): 946-956.

Ragagnin A, Ezpeleta J, Guillemain A, Boudet-Devaud F, Haeberle A M, Demais V, Vidal C, Demuth S, Beringue V, Kellermann O, Schneider B, Grant N J & Bailly Y. Cerebellar compartmentation of prion pathogenesis. Brain Pathol. 2017 Mar 07.

Voisset C, Blondel M, Jones G W, Friocourt G, Stahl G, Chedin S, Beringue V & Gillet R. The double life of the ribosome: When its protein folding activity supports prion propagation. Prion. 2017 Mar 04; 11(2): 89-97.

Martin-Lanneree S, Halliez S, Hirsch T Z, Hernandez-Rapp J, Passet B, Tomkiewicz C, Villa-Diaz A, Torres J M, Launay J M, Beringue V, Vilotte J L & Mouillet-Richard S. The Cellular Prion Protein Controls Notch Signaling in Neural Stem/Progenitor Cells. Stem Cells. 2017 Mar; 35(3): 754-765.

Van der Rest G, Rezaei H & Halgand F. Monitoring Conformational Landscape of Ovine Prion Protein Monomer Using Ion Mobility Coupled to Mass Spectrometry. J Am Soc Mass Spectrom. 2017 Feb; 28(2): 303-314.

Le Dur A, Lai T L, Stinnakre M G, Laisne A, Chenais N, Rakotobe S, Passet B, Reine F, Soulier S, Herzog L, Tilly G, Rezaei H, Beringue V, Vilotte J L & Laude H. Divergent prion strain evolution driven by PrPC expression level in transgenic mice. Nat Commun. 2017 Jan 23; 8: 14170.

Munoz-Montesino C, Sizun C, Moudjou M, Herzog L, Reine F, Igel-Egalon A, Barbereau C, Chapuis J, Ciric D, Laude H, Beringue V, Rezaei H & Dron M. A stretch of residues within the protease-resistant core is not necessary for prion structure and infectivity. Prion. 2017 Jan 02; 11(1): 25-30.


Bougard D, Brandel J P, Belondrade M, Beringue V, Segarra C, Fleury H, Laplanche J L, Mayran C, Nicot S, Green A, Welaratne A, Narbey D, Fournier-Wirth C, Knight R, Will R, Tiberghien P, Haik S & Coste J. Detection of prions in the plasma of presymptomatic and symptomatic patients with variant Creutzfeldt-Jakob disease. Sci Transl Med. 2016 Dec 21; 8(370): 370ra182.

Bernelin-Cottet C, Deloizy C, Stanek O, Barc C, Bouguyon E, Urien C, Boulesteix O, Pezant J, Richard C A, Moudjou M, Da Costa B, Jouneau L, Chevalier C, Leclerc C, Sebo P, Bertho N & Schwartz-Cornil I. A Universal Influenza Vaccine Can Lead to Disease Exacerbation or Viral Control Depending on Delivery Strategies. Front Immunol. 2016 7: 641.

Jaumain E, Quadrio I, Herzog L, Reine F, Rezaei H, Andreoletti O, Laude H, Perret-Liaudet A, Haik S & Beringue V. Absence of Evidence for a Causal Link between Bovine Spongiform Encephalopathy Strain Variant L-BSE and Known Forms of Sporadic Creutzfeldt-Jakob Disease in Human PrP Transgenic Mice. J Virol. 2016 Dec 01; 90(23): 10867-10874.

Munoz-Montesino C, Sizun C, Moudjou M, Herzog L, Reine F, Chapuis J, Ciric D, Igel-Egalon A, Laude H, Beringue V, Rezaei H & Dron M. Generating Bona Fide Mammalian Prions with Internal Deletions. J Virol. 2016 Aug 01; 90(15): 6963-75.

Moudjou M, Chapuis J, Mekrouti M, Reine F, Herzog L, Sibille P, Laude H, Vilette D, Andreoletti O, Rezaei H, Dron M & Beringue V. Glycoform-independent prion conversion by highly efficient, cell-based, protein misfolding cyclic amplification. Sci Rep. 2016 Jul 07; 6: 29116.

Armiento A, Doumic M, Moireau P & Rezaei H. Estimation from moments measurements for amyloid depolymerisation. J Theor Biol. 2016 May 21; 397: 68-88.

Chapuis J, Moudjou M, Reine F, Herzog L, Jaumain E, Chapuis C, Quadrio I, Boulliat J, Perret-Liaudet A, Dron M, Laude H, Rezaei H & Beringue V. Emergence of two prion subtypes in ovine PrP transgenic mice infected with human MM2-cortical Creutzfeldt-Jakob disease prions. Acta Neuropathol Commun. 2016 Feb 05; 4: 10.

Torrent J, Lange R, Igel-Egalon A, Beringue V & Rezaei H. Getting to the core of prion superstructural variability. Prion. 2016 10(1): 1-8.

Belondrade M, Nicot S, Beringue V, Coste J, Lehmann S & Bougard D. Rapid and Highly Sensitive Detection of Variant Creutzfeldt-Jakob Disease Abnormal Prion Protein on Steel Surfaces by Protein Misfolding Cyclic Amplification: Application to Prion Decontamination Studies. PLoS One. 2016 11(1): e0146833.


Li Q, Richard C A, Moudjou M & Vidic J. Purification and Refolding to Amyloid Fibrils of (His)6-tagged Recombinant Shadoo Protein Expressed as Inclusion Bodies in E. coli. J Vis Exp. 2015 Dec 19; (106): e53432.

Halliez S, Martin-Lanneree S, Passet B, Hernandez-Rapp J, Castille J, Urien C, Chat S, Laude H, Vilotte J L, Mouillet-Richard S & Beringue V. Prion protein localizes at the ciliary base during neural and cardiovascular development, and its depletion affects alpha-tubulin post-translational modifications. Sci Rep. 2015 Dec 18; 5: 17146.

Khalife M, Reine F, Paquet-Fifield S, Castille J, Herzog L, Vilotte M, Moudjou M, Moazami-Goudarzi K, Makhzami S, Passet B, Andreoletti O, Vilette D, Laude H, Beringue V & Vilotte J L. Mutated but Not Deleted Ovine PrP(C) N-Terminal Polybasic Region Strongly Interferes with Prion Propagation in Transgenic Mice. J Virol. 2015 Nov 25; 90(3): 1638-46.

Torrent J, Lange R & Rezaei H. The Volumetric Diversity of Misfolded Prion Protein Oligomers Revealed by Pressure Dissociation. J Biol Chem. 2015 Aug 14; 290(33): 20417-26.

Sarradin P, Viglietta C, Limouzin C, Andreoletti O, Daniel-Carlier N, Barc C, Leroux-Coyau M, Berthon P, Chapuis J, Rossignol C, Gatti J L, Belghazi M, Labas V, Vilotte J L, Beringue V, Lantier F, Laude H & Houdebine L M. Transgenic Rabbits Expressing Ovine PrP Are Susceptible to Scrapie. PLoS Pathog. 2015 Aug; 11(8): e1005077.

Ciric D, Richard C A, Moudjou M, Chapuis J, Sibille P, Daude N, Westaway D, Adrover M, Beringue V, Martin D & Rezaei H. Interaction between Shadoo and PrP Affects the PrP-Folding Pathway. J Virol. 2015 Jun; 89(12): 6287-93.

Floriot S, Vesque C, Rodriguez S, Bourgain-Guglielmetti F, Karaiskou A, Gautier M, Duchesne A, Barbey S, Fritz S, Vasilescu A, Bertaud M, Moudjou M, Halliez S, Cormier-Daire V, Hokayem J E, Nigg E A, Manciaux L, Guatteo R, Cesbron N, Toutirais G, Eggen A, Schneider-Maunoury S, Boichard D, Sobczak-Thepot J & Schibler L. C-Nap1 mutation affects centriole cohesion and is associated with a Seckel-like syndrome in cattle. Nat Commun. 2015 Apr 23; 6: 6894.

Torrent J, Vilchez-Acosta A, Munoz-Torrero D, Trovaslet M, Nachon F, Chatonnet A, Grznarova K, Acquatella-Tran Van Ba I, Le Goffic R, Herzog L, Beringue V & Rezaei H. Interaction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases. Acta Neuropathol Commun. 2015 Apr 03; 3: 18.

Galloux M, Gabiane G, Sourimant J, Richard C A, England P, Moudjou M, Aumont-Nicaise M, Fix J, Rameix-Welti M A & Eleouet J F. Identification and characterization of the binding site of the respiratory syncytial virus phosphoprotein to RNA-free nucleoprotein. J Virol. 2015 Apr; 89(7): 3484-96.

Ciric D & Rezaei H. Biochemical insight into the prion protein family. Front Cell Dev Biol. 2015 3: 5.


Cassard H, Torres J M, Lacroux C, Douet J Y, Benestad S L, Lantier F, Lugan S, Lantier I, Costes P, Aron N, Reine F, Herzog L, Espinosa J C, Beringue V & Andreoletti O. Evidence for zoonotic potential of ovine scrapie prions. Nat Commun. 2014 Dec 16; 5: 5821.

Halliez S, Reine F, Herzog L, Jaumain E, Haik S, Rezaei H, Vilotte J L, Laude H & Beringue V. Accelerated, spleen-based titration of variant Creutzfeldt-Jakob disease infectivity in transgenic mice expressing human prion protein with sensitivity comparable to that of survival time bioassay. J Virol. 2014 Aug; 88(15): 8678-86.

Halliez S, Jaumain E, Huor A, Douet J Y, Lugan S, Cassard H, Lacroux C, Beringue V, Andreoletti O & Vilette D. White blood cell-based detection of asymptomatic scrapie infection by ex vivo assays. PLoS One. 2014 9(8): e104287.

Halliez S, Passet B, Martin-Lanneree S, Hernandez-Rapp J, Laude H, Mouillet-Richard S, Vilotte J L & Beringue V. To develop with or without the prion protein. Front Cell Dev Biol. 2014 2: 58.

Lacroux C, Comoy E, Moudjou M, Perret-Liaudet A, Lugan S, Litaise C, Simmons H, Jas-Duval C, Lantier I, Beringue V, Groschup M, Fichet G, Costes P, Streichenberger N, Lantier F, Deslys J P, Vilette D & Andreoletti O. Preclinical detection of variant CJD and BSE prions in blood. PLoS Pathog. 2014 Jun; 10(6): e1004202.

Bellon A, Comoy E, Simoneau S, Mornac S, Dehen C, Perrin A, Arzel A, Arrabal S, Baron H, Laude H, You B, Deslys J P & Flan B. Decontamination of prions in a plasma product manufacturing environment. Transfusion. 2014 Apr; 54(4): 1028-36.

Makzhami S, Passet B, Halliez S, Castille J, Moazami-Goudarzi K, Duchesne A, Vilotte M, Laude H, Mouillet-Richard S, Beringue V, Vaiman D & Vilotte J L. The prion protein family: a view from the placenta. Front Cell Dev Biol. 2014 2: 35.


Moudjou M, Sibille P, Fichet G, Reine F, Chapuis J, Herzog L, Jaumain E, Laferriere F, Richard C A, Laude H, Andreoletti O, Rezaei H & Beringue V. Highly infectious prions generated by a single round of microplate-based protein misfolding cyclic amplification. MBio. 2013 Dec 31; 5(1): e00829-13.

Laferriere F, Tixador P, Moudjou M, Chapuis J, Sibille P, Herzog L, Reine F, Jaumain E, Laude H, Rezaei H & Beringue V. Quaternary structure of pathological prion protein as a determining factor of strain-specific prion replication dynamics. PLoS Pathog. 2013 9(10): e1003702.

Li Q, Chevalier C, Henry C, Richard C A, Moudjou M & Vidic J. Shadoo binds lipid membranes and undergoes aggregation and fibrillization. Biochem Biophys Res Commun. 2013 Aug 30; 438(3): 519-25.

Oumata N, Nguyen P H, Beringue V, Soubigou F, Pang Y, Desban N, Massacrier C, Morel Y, Paturel C, Contesse M A, Bouaziz S, Sanyal S, Galons H, Blondel M & Voisset C. The toll-like receptor agonist imiquimod is active against prions. PLoS One. 2013 8(8): e72112.

Segarra C, Bougard D, Moudjou M, Laude H, Beringue V & Coste J. Plasminogen-based capture combined with amplification technology for the detection of PrP(TSE) in the pre-clinical phase of infection. PLoS One. 2013 8(7): e69632.

Menon R P, Nethisinghe S, Faggiano S, Vannocci T, Rezaei H, Pemble S, Sweeney M G, Wood N W, Davis M B, Pastore A & Giunti P. The role of interruptions in polyQ in the pathology of SCA1. PLoS Genet. 2013 9(7): e1003648.

Halliez S, Chesnais N, Mallucci G, Vilotte M, Langevin C, Jaumain E, Laude H, Vilotte J L & Beringue V. Targeted knock-down of cellular prion protein expression in myelinating Schwann cells does not alter mouse prion pathogenesis. J Gen Virol. 2013 Jun; 94(Pt 6): 1435-40.

Chakroun N, Fornili A, Prigent S, Kleinjung J, Dreiss C A, Rezaei H & Fraternali F. Decrypting Prion Protein Conversion into a beta-Rich Conformer by Molecular Dynamics. J Chem Theory Comput. 2013 May 14; 9(5): 2455-2465.

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Xiao X, Yuan J, Haik S, Cali I, Zhan Y, Moudjou M, Li B, Laplanche J L, Laude H, Langeveld J, Gambetti P, Kitamoto T, Kong Q, Brandel J P, Cobb B A, Petersen R B & Zou W Q. Glycoform-selective prion formation in sporadic and familial forms of prion disease. PLoS One. 2013 8(3): e58786.

Cavaliere P, Pagano B, Granata V, Prigent S, Rezaei H, Giancola C & Zagari A. Cross-talk between prion protein and quadruplex-forming nucleic acids: a dynamic complex formation. Nucleic Acids Res. 2013 Jan 07; 41(1): 327-39.

Cavaliere P, Torrent J, Prigent S, Granata V, Pauwels K, Pastore A, Rezaei H & Zagari A. Binding of methylene blue to a surface cleft inhibits the oligomerization and fibrillization of prion protein. Biochim Biophys Acta. 2013 Jan; 1832(1): 20-8.


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Cronier S, Carimalo J, Schaeffer B, Jaumain E, Béringue V, Miquel MC, Laude H, Peyrin JM. Endogenous prion protein conversion is required for prion-induced neuritic alterations and neuronal death. FASEB J. 2012 Sep;26(9):3854-61. Epub 2012 Jun 1.

Passet B, Young R, Makhzami S, Vilotte M, Jaffrezic F, Halliez S, Bouet S, Marthey S, Khalifé M, Kanellopoulos-Langevin C, Béringue V, Le Provost F, Laude H, Vilotte JL. Prion protein and Shadoo are involved in overlapping embryonic pathways and trophoblastic development. PLoS One. 2012;7(7):e41959. Epub 2012 Jul 30.

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Beck KE, Sallis RE, Lockey R, Vickery CM, Béringue V, Laude H, Holder TM, Thorne L, Terry LA, Tout AC, Jayasena D, Griffiths PC, Cawthraw S, Ellis R, Balkema-Buschmann A, Groschup MH, Simmons MM, Spiropoulos J. Use of murine bioassay to resolve ovine transmissible spongiform encephalopathy cases showing a bovine spongiform encephalopathy molecular profile. Brain Pathol. 2012 May;22(3):265-79. Epub 2011 Oct 13.

Petit-Paitel A, Ménard B, Guyon A, Béringue V, Nahon JL, Zsürger N, Chabry J. Prion protein is a key determinant of alcohol sensitivity through the modulation of N-methyl-D-aspartate receptor (NMDAR) activity. PLoS One. 2012;7(4):e34691. Epub 2012 Apr 20.

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 ==> Open access:     Abstract         Full text           PDF
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Modification date: 02 July 2024 | Publication date: 19 May 2009 | By: D Martin